Tuesday, 8 April 2025

Alflutop

 Alflutop is a product that I wish I had known about a long time ago. I would not have had the 30 plus cortisone injections I was given throughout my career if I had known about Alflutop. I would have taken this product instead. Cortisone weakens ligaments and tendons, and in my opinion, is one of the main reasons why I have ruptured so many body parts. Alflutop on the other hand, reduces inflammation, but also encourages repair and regeneration of cartilage and connective tissue. For these reasons, Alflutop is reported to be more effective than corticosteroid injections.


Alflutop is a natural, injectable formula. The active substance of Alflutop is a bioactive concentrate derived from small marine fish, which has anti-inflammatory and regenerative effects on tissues. The concentrate also contains mucopolysaccharides (chondroitin sulfate), amino acids, peptides, ions of sodium, potassium, calcium, magnesium, iron, copper and zinc.


Alflutop inhibits hyaluronidase, an enzyme that breaks down hyaluronic acid, a crucial component of joint fluid that maintains lubrication and joint health. It also promotes the biosynthesis of hyaluronic acid and other compounds essential for restoring cartilage structure and function. It stimulates chondrocytes which are cells responsible for cartilage production. It is anti-inflammatory, has analgesic effects, and has antioxidant properties that protects the negative effects of oxidative stress and reactive oxygen species that contribute to joint damage.


Alflutop has proven effective in clinical trials in degenerative joint disorders (bursitis, tendonitis, and arthritis). Studies have shown that Alflutop can relieve pain, improve joint function, and stop the progression of degeneration in the joint. It has been successful in knee and hip osteoarthritis. Alflutop is a chondroprotector.


Alflutop is also effective in treating chronic lower back pain by inhibiting TNF-α expression, which significantly correlates with a decrease in neuropathic pain syndrome. It is also beneficial in spondylosis which is degenerative changes in the spine, often associated with osteoarthritis. The condition is characterized by the breakdown of the vertebral column, primarily affecting the vertebral bodies, the neural foramina, and the facet joints. This degenerative process can lead to the formation of bone spurs, which may cause compression of spinal nerves or the spinal cord, resulting in symptoms such as pain, numbness, or weakness in the arms or legs.


Another condition that is helped by Alflutop is osteochondrosis. This is a group of disorders that affect the growing skeleton, particularly in children and adolescents. Osteochondrosis can affect various parts of the body, including the hip, knee, foot, elbow, and back. Common types include Legg-Calvé-Perthes disease, Osgood-Schlatter disease, Sinding-Larsen-Johansson syndrome, and Sever's disease.

  

Alflutop comes in 10 vials and is administered via intramuscular injection. They also do intra-articular injections but personally, I would stick to intramuscular unless you have an experienced practitioner who is using a guided ultrasound for the intra-articular. I just don’t think the risk is worth it.


A general recommended dosage for intramuscular administration is to take 1ml every day for 20 days. Alternatively, you could take 2ml every other day (10 injections over 20 days).


Alflutop can be used to prevent the breakdown of cartilage and joints, to manage osteoarthritis and similar conditions if they have already progressed, and you can use Alflutop for any injury to the joints and even post-surgery to help speed up recovery.

 

If you would like to purchase Alflutop, feel free to contact us and we can give you details to a good supplier.


References / further reading:

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DMSO - Dimethyl sulfoxide

 DMSO - Dimethyl sulfoxide


To begin with, I strongly suggest you read the further reading links as those articles are much more in depth than I am going to explain here and it is also the main source of the information I am going to talk about. This is basically my understanding / takeaway of the references listed below, use cases that are relevant to me, and a way for me to explain the potential benefits of DMSO to my clients in a simple manner.


DMSO is an organic solvent with a variety of pharmaceutical actions, including analgesic, diuretic, bacteriostatic, membrane-penetrant, anti-inflammatory, antioxidant, vasodilatory, softens scar tissue, anti-clotting, cholinesterase inhibitory effects, radioprotectant, and cytoprotective effects. It has been studied for over 50 years. It shows potential benefits in so many conditions it is hard to list. These include stroke, TBI, dementia, heart attack, arthritis, sports injuries, pain management, and so much more.


DMSO has a long history. It can be found throughout nature, found in many fruits and vegetables. It is a by-product of the paper-making process and was first synthesized in 1866 by the Russian scientist Alexander Zaytsev. Its use in medicine dates to around the 1960’s through the work of Dr Stanley Jacob.


DMSO can help speed up the healing of many types of injuries. This is a huge benefit to us as we train many athletes and we have many tools to help speed up healing and recovery. DMSO is another effective tool we add to treatment protocols as it is safe and works very well. It can be applied topically, taken orally, or even given intramuscularly and intravenously. When applied topically you can also add other nutrients that help the healing process as DMSO helps transport them into, and throughout the body. This works better for smaller molecules like vitamin C for example. DMSO can help both micro-injuries and more traumatic injuries. Its ability to prevent scar tissue formation, break it down, and prevent adhesions, also helps athletes recover from day-to-day training sessions.


DMSO works best when it is applied quickly after an injury, within the first 3-4 days. Reports from doctors and athletes who used DMSO back in the 1960’s and 70’s, have said that it works 70-80% of the time. Players had reported that they could return to the field 50-75% faster when they used DMSO, compared to when they had suffered similar injuries in the past without using DMSO.


DMSO is also useful for our older clients who may have some arthritis. It helps relieve pain and it can also increase circulation and remove excess fluid from where it doesn’t belong. On top of this, it can help remove clots. So, anyone with any risk factors for heart disease or stroke can benefit from the use of DMSO as well.

 

DMSO can also speed up wound healing, prevent wounds from getting infected, eliminate pain, and prevent the formation of scar tissue or dissolve it once present. These properties are very relevant with the sports we deal with and also for anyone undergoing surgery of any sort. Treating scars is very important but often overlooked. DMSO can speed up the healing of these scars helping tissue return to full function.


Another beneficial area of use is in TBI and concussion. Rugby league is a contact sport and certain things are inevitable. Using DMSO as part of a prevention, and also recovery protocol can speed up healing, improving any memory issues and reducing headaches as an example. Dr. Stanley Jacob explains, “DMSO is a potent free-radical scavenger and diuretic that reduces swelling and improves blood supply to the brain. This improves blood oxygenation to brain tissue. Injured brain cells often aren’t dead. When these cells get increased blood supply and more oxygen, and when the free radicals are scavenged, dying cells can recover, and brain swelling is reduced very rapidly.” He also says “we observed that when the human brain was treated with intravenously administered DMSO after a head injury, the swelling could be reduced within five minutes. No other treatment comes close to acting that quickly. In patients given other commonly used therapeutic agents such as intravenous barbiturates, the brain continued to swell. We’ve known about DMSO’s efficacy for this type of injury for a long time.” This was from studies conducted in 1978-1982. Dr Jacob says that nothing comes close to DMSO in terms of efficacy.


DMSO can also help with dementia, Alzheimer’s, Parkinson’s and recovery from stroke. Given soon after a stroke, DMSO can dissolve the clot that causes the stroke, restoring circulation and avoiding paralysis. DMSO helps to remove the excess fluid from the brain resulting in lower pressure and less brain damage. DMSO also protects nerve cells from any disruption following stroke injury. This is very beneficial to know as we train a lot of older clients who either have these issues or have suffered a stroke in the past.


The same goes for our clients who have suffered a heart attack. DMSO can reduce the amount of permanently damaged tissue following a heart attack. It can also maintain the heart’s ability to circulate blood when its blood supply is cut off.


Most of the benefits of DMSO probably come from it’s anti-inflammatory and anti-oxidative properties, along with its ability to increase circulation, relax muscles, block pain signals, and protect cells from death (e.g. neurons). Increasing the cell’s ability to produce ATP also explains some of DMSO’s protective effects and its anti-cancer effects. DMSO is able to pass through biological membranes without damaging them.

  

DMSO rapidly enters the bloodstream regardless of the route of administration. “within 5 minutes after going on the skin it can be found in the blood, and within an hour it can be found within the bones), but simultaneously does not accumulate within the body after prolonged use (and virtually none remains a week after administration).” 


Another benefit to DMSO is that it is very safe. NSAIDs, opioids, and other pain medications come with a host of problems. A group of nerves in the body known as “small fibers” transmit specific sensations and are linked to chronic pain syndromes. DMSO blocks the conduction of these smaller fibers, stopping pain without damaging the rest of the body. DMSO is also anti-inflammatory as mentioned above, and it can relax skeletal muscle which can also help relieve pain. There is no tolerance built up to using DMSO either. DMSO can become more effective over time.


To sum up, DMSO can be used to help with many different issues:


  • Sports injuries – bursitis, tendonitis, sprains / strains / contusions, soft tissue tears, tendon and ligament injuries, meniscus injuries, fractures, lumbar disc disorders

  • Pain management – arthritis (rheumatoid and osteo), cancer pain, headaches, spinal / back pain, surgical pain, gout, restless leg syndrome, fibromyalgia

  • Wound healing – burns, ulcers, surgical wounds, scar tissue and adhesions, skin grafts etc.

  • Neurological disorders – strokes, spinal cord injuries, dementia, Alzheimer’s, Parkinson’s, Down Syndrome, developmental delay, TBI, concussion, epilepsy

  • Circulatory disorders – heart attack, atherosclerosis, varicose veins,

  • Autoimmune conditions – interstitial cystitis, asthma, IBD, ulcerative colitis, multiple sclerosis

  • Vision – macular degeneration, cataract, glaucoma, retinosa pigmentosa

  • Protein folding – ensures protein stability, helps eliminate misfolded proteins, helps with amyloidosis, cystic fibrosis


DMSO is protective of cells throughout the body. DMSO has been shown to:


  • DMSO quickly heals a wide variety of musculoskeletal injuries, treats a variety of joint disorders (e.g rheumatoid arthritis), and is a safe and effective pain killer.

  • Protect tissue from dying when blood supply is cut off. Prevent reperfusion injury (an injury that can happens when blood supply returns to tissue. Prevent the formation of clots when blood is restored. Reduce the amount of permanently damaged tissue following a myocardial infarction and maintain the heart’s ability to circulate blood when its blood supply is cut off.

  • Increase the production of ATP in cells, which likely both accounts for some of DMSO’s protective effects and its anticancer effects.

  • Save the fingers of individuals with severe frostbite that would otherwise require amputation.

  • Treat all different types of burns, including sunburn. People have said it helped sunburn in 10-30 minutes after application. In burns, DMSO stopped pain, prevented blisters, and allowed skin to fully recover. 

  • Protect cells from being damaged by radiation.

  • Neutralize free radicals.

  • DMSO is beneficial in circulatory disorders. It can increase circulation and eliminate clots for example. It also removes edema and excess fluid from where it doesn’t belong. This is beneficial in many injuries to the joint, and tendons for example, where blood supply can be limited. Diabetic ulcers, peripheral neuropathy, varicose veins, can all be helped by DMSO. Some doctors have even successfully treated heart attacks with DMSO.

  • DMSO can be beneficial in the treatment and management of strokes. The most benefit was seen when DMSO was given immediately after a stroke but DMSO was still able to save neurons long after the stroke had happened. IV would be ideal but not always practical. DMSO applied topically to the head within minutes and followed up by an intramuscular injection had helped one lady survive a stroke. Treatment continued for another week after the stroke, topically, intramuscular, and orally.

  • DMSO helps traumatic brain injury (TBI) and concussions. It can help prevent concussions and improve recovery. Even 13 years post-concussion, one lady received an injection of DMSO and had an immediate improvement in memory issues and foggy headaches.

  • DMSO may help with cognitive impairment, dementia, Alzheimer’s, and Parkinson’s. 

  • DMSO lowers many inflammatory cytokines

  • There has even been cases where DMSO has helped people walk again after spinal cord injuries. Like strokes, the greatest benefit from DMSO is seen if it is given (intravenously) within 90 minutes of the injury. These are reports and from animal studies, no formal studies on DMSO after spinal injuries have been conducted in humans. 

  • DMSO helps with protein folding. Misfolded proteins are thought to play a role in many chronic diseases.

  • DMSO has helped with developmental disabilities such as Down Syndrome.

 

 

 

References / further reading:

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